Red Cell Distribution Width and the Risk of Death in Middle-aged and Older Adults

Red Cell Distribution Width and the Risk of Death in Middle-aged and Older Adults

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Red cell distribution width RDW , a component of an electronic complete blood count, is a measure of heterogeneity in the size of circulating erythrocytes. However, it has not been demonstrated that RDW is a predictor of mortality independent of nutritional deficiencies or in the general population. RDW was measured in a national sample of community-dwelling adults aged 45 and older who participated in the — National Health and Nutrition Examination Survey; mortality follow-up occurred through December 31, Higher RDW values were strongly associated with an increased risk of death.

Compared to the lowest quintile of RDW, the following were adjusted hazard ratios HR for all-cause mortality and 95 percent confidence intervals : second quintile, 1. The prognostic effect of RDW was observed in both middle-aged and older adults for multiple causes of death.

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